Please use this identifier to cite or link to this item: https://oar.tib.eu/jspui/handle/123456789/4628
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Title: Photoactivatable Hsp47: A tool to control and regulate collagen secretion & assembly
Authors: Khan, EssakSankaran, ShrikrishnanPaez, JulietaMuth, ChristinaHan, Mitchelldel Campo, Aránzazu
Publishers Version: https://doi.org/10.26434/chemrxiv.6964703.v1
Issue Date: 2018
Published in: ChemRxiv
Publisher: ChemRxiv
Abstract: Hsp47 is a chaperone protein with a fundamental role in the folding, stability and intracellular transport of procollagen triple helices. A light-responsive Hsp47 recombinant protein, engineered to control in situ the production and assembly of cellular collagen is here demonstrated. This novel light-driven tool enables unprecedented fundamental studies of collagen biosynthesis and associated diseases.
DDC: 540
License: CC BY-NC-ND 4.0 Unported
Link to License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Appears in Collections:Chemie



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