Please use this identifier to cite or link to this item: https://oar.tib.eu/jspui/handle/123456789/6018
Files in This Item:
File Description SizeFormat 
Schmidt2020.pdf8.11 MBAdobe PDFView/Open
Title: Engineering microrobots for targeted cancer therapies from a medical perspective
Authors: Schmidt, Christine K.Medina-Sánchez, MarianaEdmondson, Richard J.Schmidt, Oliver G.
Publishers Version: https://doi.org/10.1038/s41467-020-19322-7
Issue Date: 2020
Published in: Nature Communications Vol. 11 (2020)
Publisher: Berlin : Springer Nature
Abstract: Systemic chemotherapy remains the backbone of many cancer treatments. Due to its untargeted nature and the severe side effects it can cause, numerous nanomedicine approaches have been developed to overcome these issues. However, targeted delivery of therapeutics remains challenging. Engineering microrobots is increasingly receiving attention in this regard. Their functionalities, particularly their motility, allow microrobots to penetrate tissues and reach cancers more efficiently. Here, we highlight how different microrobots, ranging from tailor-made motile bacteria and tiny bubble-propelled microengines to hybrid spermbots, can be engineered to integrate sophisticated features optimised for precision-targeting of a wide range of cancers. Towards this, we highlight the importance of integrating clinicians, the public and cancer patients early on in the development of these novel technologies.
Keywords: chemotherapy; cancer; microrobots
DDC: 610
License: CC BY 4.0 Unported
Link to License: https://creativecommons.org/licenses/by/4.0/
Appears in Collections:Medizin



This item is licensed under a Creative Commons License Creative Commons